Noticeably happier and energetic. for severe Gastro-Intestinal issues. APOQUEL (oclacitinib) manufactured by Zoetis, I have also let my daughter know as she has 2 Doxies on it for itching and allergies as well. 2 packs of apoquel tablets I do want to note that when he first started on the apoquel, it worked really well. She is Am. I just feel I needed to share these issues just in case anyone else has a pet that is suffering these same or similar symptoms. JA: Hi there. 5 days on Apoquel and she went to the kennel. Never told that it destroyed the immune system or the side effects. immune-mediated disease. When we get to 12 months the doctor may reduce her meds. Early Tuesday Nov 21 my husband woke me up to tell me that Ginny had let put a help and was very weak and could not stand up on her own. please do not give your pets this drug. Does zonisamide interact with my other drugs? There are also no drug Apoquel alternatives for dogs that are effective and safe. (Answered 2023), Is It Legal to Eat Dog Meat in Canada? He has had 3 doses of apoquel and I decided to research side effects when I noticed him being lethargic. He also had these side effects while taking hydroxyzine. He is a different dog entirely now that his life isnt consumed by itchiness and chewing and scratching. Upon receiving your complaint, the drug company will have to submit a report of adverse drug experience to the FDA. I took her back to the vet in November as I was so concerned about the weight gain. of the development of severe pyoderma (after day 19) and one dog withdrew because of the The reports of the studies list everything that the animals in the studies had while in the study, but a causative relationship cannot be made, merely an association . But the principle is to think simple, minimal ingredients, avoid artificial colors, flavors and preservatives. 5 days later & I still have a very very different dog He went from an extremely confident, friendly & vocal dog who was running round & playing all the time with my other dog into & nervous wreck & he also seems to still have discomfort in his bad leg. The safety and efficacy of Apoquel has not been evaluated in humans, and it is not recommended for use in people. was hospitalized for cystitis secondary to urolithiasis (after day 80 of therapy). People need to look at tbeir vetwhat has been tried first. I have a 5 yr old Yorkie/Poodle. (Answered 2023). I agree. Fortunately many other pet owners think otherwise. Apoquel has been shown to be effective in reducing clinical signs of atopic dermatitis, such as pruritus, erythema, and scaling, within 24 hours of administration, Dr. Silva says. I WOULD NOT recommend giving Apoquel to your pet!! We inquired on several occasions if Apoquell would have caused all of this and were reassured it would not. How to Report Apoquel Side Effects in Dogs Apoquel side effects in dogs can be reported directly to the manufacturing company. other than his allergies he is healthy, happy, and spoiled rotten. After 3 days we stopped the medication because her organs were shutting down. He keep vomiting and now cant You may want to remember the golden rule..if you dont have anything nice to say, then dont say anything at all. There should be some mornings to the vets, but there arent. Moderate Interactions. He has been on this drug for three years and his allergies are gone. We were told to take her home and scheduled a full body scan by a professional x-ray tech. Maybe, but now she will have to fight Cancer and at 10 1/2, probably not much we can or I can afford to do. We are devastated. My question is whether there is any relationship between the Apoquel and tremors. Im sure Zoetis doesnt want law suits so Im sure theyve doe their research. Stopped drinkingeatingswollen abdomen (Ascites)low albumin is to blame for swelling.proteinuriadiagnosis of Protein Losing Nephropathy. Thank you Dr. Jones, youre one of the good ones. I AM STOPPING THIS MED TODAY! We rescued our Min Pin Buddy 8 yrs ago. That is when I found all the other comments with the other symptoms she had. Just please dont pump them with drugs, there is no magic pill but with research Im sure you too can find a natural solution that will help. A little research showed that the Rx was twice the recommended amount for her. We put my boy on it and yes, it did work great. So, its impossible to recommend across the board dosages that will produce good results. She is on Natural Balance fish and sweet potato formula and same brand of treats as she is allergic to wheat, gluten, chicken and beef. . looks great but also is sseems to want more attention than usual She did not tell me the dangerous side effects, she did not give me a print out of this information. My dog was prescribed this medication and quickly developed a serious urinary tract infection. After the allergy tests I gave him Natural Balance Sweet Potato and Fish, which he doesnt eat much so I add other things to it. You will need to work closely with your vet to find the treatment regime that works best for your pooch. Our vet is pleased with her results but wants us to try and switch to a different medication because she does not know the long term affects of Apoquel. He is now on phenobarbital for life because the seizures never went away. We had no choice but to euthanize him early this morning. He is a cocker spaniel who is now just over 10 years old. P.S. In simple terms, apoquel changes how the immune system acts. My German Shepherd started on Apoquel about five months ago. Strange about aggression as a side effect could it be she just doesnt feel good on the drug and irritable? Sign up to receive only the most important updates straight to your inbox. Vet suggested Apoquel. to determine what has happened. Hope FDA takes this seriously as theres always the money making issue versus quality/safety now days. Last night was the first dose. And now me and my family have the heartache of thinking we was helping his allergy problem whenever this drug was killing him on the inside, please dont use this drug, no one wants there fur baby to die over a wrong decision a vet makes. Just seems like a lot to me. He is about 3 yrs old. Apoquel can be given with or without food. Hydroxyzine HCI tablets are available by veterinary prescription for dogs. She keeps getting infections in her anal gland area. As I write this my 4 month old puppy is in ICU getting I.V. Health events associated with the drug were difficult to compare between groups given the low number of dogs in the placebo group at the end of the study. More serious side effects can include coma and apnea. But, I did notice your office carried CET chews, Metacam, and Baytril. Zoetis has made a fortune on this drug, it is time to stop the suffering. It does seem that the shot and the baytril will make her infection go away and allergies better at least for awhile. These medications may cause some risk when taken together. They are making Millions off this.?? We immediately stopped the apoquel and he has never had a seizure since. (2023), How Long After Color Remover Can I Bleach My Hair? Another prescription for Apoquel 5.4mg 70 tablets were dispensed to us for $126.00 Since August 2018 when we discontinued giving Aries Apoquel, there are a few papillomas of small size but nothing like was spreading all over his body. I fear he may die! Apoquel can be used along with: antibiotics antifungals anti-arthritis drugs I am so grateful to have her but feel bad as she has to take 570 pills every month plus liquid medication, mostly due to her size. I have had her since she was 6 mths old and she is now an old lady at 13. After one week on BID dosing he had a 5min seizure, I just chalked it up to stress. Was told her prognosis is poor. Our dog is now on a special food do decrease bladder and urinary tract infections. She had a check up and we were told everything was good. My vet says its allergies causing it. Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used by veterinarians as a supportive treatment for the relief of arthritic symptoms in geriatric dogs. It especially targets the immune system. We gave her omega fatty acids, removed the grass out of our yard and eliminated environmental threats the best we could. Every dog is different, so you have to try different foods; there is not just ONE right food. But, sometimes this is the desired outcome. Apoquel starts relieving allergic dog itch and inflammation due to skin allergies within 4 hours and controls it within 24 hours. I at least know for sure 1 drug I would Never Try and that is this Apoquel !! Hydroxyzine for dogs is not often used in this capacity. My Yorkie/jack Russell, around 8 years old is supposedly allergic to fleas, around 20lbs. A typical dose is 1 mg per pound in dogs every 6-8 hours. If these sort of dermatologic/parasitic overgrowths occurred in humans from treatment with JK inhibitors, it would certainly prompt the FDA to take action to protect the patient population utilizing these medications from these severe adverse events Last June 2016 our vet prescribed Apoquel for our 8 year old Shih Tzu for her itching. I was aware of the risks involved with this drug and was well informed both by my vet and also by my own research before beginning his treatment. It worked almost immediately. Its been about 21 hours since he had a pill, so Im hoping that by tomorrow morning, its out of his system. Thank you all, positive & negative on Aproquel. If you are looking for a quick and easy way to help your dogs allergies, I suggest you try my supplement, Dr Jones Ultimate Canine Health Formula. No rain water from puddles or park ponds, rinse off feet every time after walks during summer fall months, Al-Gen drops (Genestra) 1 month. As a result, hydroxyzine pamoate is what doctors will prescribe to human patients to treat anxiety. eat, no appetite, and started throwing up. The vitamins actually made him strong not to get the seasonal allergies so bad. Apoquel helps him -100%, bur increase thirst and he urinated more often then normally. He has been on Prednisone since he was 10. Just as I was dozing off, she abruptly sat up and started crying. After this it was too late for her they said she had I have documented this story on my blog at atozwithashley.com. Apoquel may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. My chocolate lab has been on Apoquel for years now. Youll also want to think about whether you want to give your dog a pill or liquid form of the medication, and how often youll need to give the medication. These beneficial bacteria play a role in normalizing the overactive immune system. After reading the comments here I will not be continuing on Apoquel. Benadryl helps his runny nose and itchy eyes, but he was still scratching himself nonstop. I was never told this drug is an immunosuppressent. Thank you for this eye opening site, so important to be informed on the dangers os all meds. We need our own check list to take a survey on this drug. I am still waiting for a call back. This is because your vet will be able to advise you on the best course of action for your dog based on their individual health and medical history. He suffers from allergies also. He also gets half a Zyrtec morning and night. I would say that these veterinarians are concerned about their wallets Just to note a couple of ignorant owners from the above blog. So, our story is our 7 mo. I took him back off of it and I called the vet and I said that I want to put him back on the pred. After reading these post Im convinced its the Apoquel. It took about 3 months for her red blood cells to start reproducing and return to normal. One morning about 5AM she woke me standing up on the bed and she froze and fell off the bed like a statue and had a seizure. I have had her and my other dogs on a special diet but it still doesnt help. After reading almost all of the comments on here I would think you would all exchange info and file a Class Action Lawsuit against the makers of this drug, the FDA for negligence, at least. His breathing labored at times and a runny nose. My 10 year old Maltese 10 pound has had intermittent allergy problems his entire life. Tried Benydry but it only made him groggy. My dog died this past Sunday and had all of the Symtoms I have seen in most of this comments, he was clumsy and peed in weird places out of nowhere I knew what my dog ate and how heathy he was until this drug was giving to him. Some of the horror stories above are frightening. She couldnt eat on her own and worst, she didnt recognize us or let us pet her. My 11 Yorkie mix has had allergiesitchy feet mostly but all over at times, that we have tolerated as holisticly as possible his whole lifewith the occasional Benadryl. He now has a tumor on his neck ( just removed and sent for histopatholgy). Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. What is hydroxyzine? Of the total drug interactions, 98 are major, 282 are moderate, and 4 are minor. I have read that this could be a side effect of apoquel which I was not made aware. Dr Jones. She was also drinking more and having accidents. In April he received Lyme vaccine and shortly thereafter developed skin infection requiring steroids. I came on the web to find if there might be a correlation as to what I am seeing with my dog and the drug Apoquel. While still within reference ranges, mean serum globulin and mean white blood cell, The vet kept urging us to put her on it, that the side effects would be mild and should disappear. My 6 y/o German shepherd was on this drug for approximately 8 weeks and is now deceased. It is a symptom of an underlying disease or condition. 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To 12 months the doctor may reduce her meds to 12 months the doctor may reduce her.! That the shot and the Baytril will make her infection go away and allergies better at for! Colors, flavors and preservatives role in normalizing the overactive immune system on Aproquel the here! Effects can include coma and apnea drug company will have to try different foods ; there any.