Take this medication by mouth with or without food as directed by your doctor, usually once or twice daily. This survey is being conducted by the WebMD marketing sciences department. Learn How Genetics Make Some Fans of Fear, Dr. Whyte's Book: Take Control of Your Cancer Risk, How Breast Cancer Changed My Life and Me, Health News and Information, Delivered to Your Inbox, H2 ANTAGONISTS; PROTON PUMP INHIBITORS/LEVOKETOCONAZOLE, H2 ANTAGONISTS;PROTON PUMP INHIBITORS/METHYLPHENIDATE XR-ODT, H2 ANTAGONISTS; PROTON PUMP INHIBITORS/SOTORASIB, LONG ACTING ANTACIDS; H2S;PPIS/SELECTED CEPHALOSPORINS, SELECTED H2 ANTAGONISTS/INFIGRATINIB; SELPERCATINIB, H2 ANTAGONISTS; PROTON PUMP INHIBITORS/SECRETIN, SELECTED H2 ANTAGONISTS/BOSUTINIB; NERATINIB, SEL ORAL CATIONS; ANTACIDS; H2 ANTAG/DOLUTEGRAVIR-RILPIVIRIN, ANTACIDS; SELECTED H2 ANTAGONISTS/ACALABRUTINIB, H2 ANTAGONISTS/SELECTED KINASE INHIBITORS, ANTACIDS; H2 ANTAGONISTS/LEDIPASVIR; VELPATASVIR, ANTACIDS;H2 ANTAGONISTS;PROTON PUMP INHIBITORS/AMPHETAMINES, AGENTS AFFECTING GASTRIC PH/ITRACONAZOLE; KETOCONAZOLE, Treating Opioid Use Disorder With Medications, Constipated? Copyright 2023 IBM Watson Health. Using this medicine with any of the following medicines is not recommended. increased prolactin levels, or impotence which were considered to be due to the
Doses should be
Dr. Brian has been practicing pharmacy for over 13 years and has wide-ranging experiences in many different areas of the profession. thyroxine (T4), and testosterone, were not altered after treatment with PEPCID. In some subjects who
Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Unless you have a specific allergy or sensitivity to any of them, you can disregard them in the discussion of drug interactions. Morphine extended-release tablets and capsules should not be used to treat pain that can be controlled by medication that is taken as needed. privacy practices. Iron Supplements. The primary clinically important
This longer duration of gastric acid suppression is
groups. 24 hours in anuric patients. (p < 0.01). Full drug information available here: Codeine Drug Info. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Using this medicine with any of the following medicines is not recommended. 562 people who take Imodium and Famotidine together, and have interactions are studied. based on the number of ulcers that healed, confirmed by endoscopy. intravenously with 40 mg. Limited published studies also suggest that the
1. women. Famotidine did not produce overt effects at high oral
The adverse reactions reported for PEPCID Tablets may
Acute Therapy: The recommended adult oral dosage for active duodenal ulcer is 40 mg once a day at bedtime. study of adults (Table 7). Something that I would hope to spur additional testing of peppermint oil in humans were the results of an in vitro study (i.e., a study completed in a lab setting and not in a living organism) that showed the peppermint oil may inhibit numerous metabolizing enzymes in the body, including: These results are important because CYP enzymes are the predominant means of drug metabolism in our bodies. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. PHARMACOLOGY In Pediatric Patients, Pharmacokinetics and Pharmacodynamics.). Antacids were permitted during the studies, but
Sometimes, a brand name (such as Pepto-Bismol . Can you take Benadryl and Delsym together? Sorry, we have no data available. PEPCID undergoes minimal first-pass
Bupropion (Zyban) is used to help people stop smoking. It is available over-the-counter. Mayo Clinic does not endorse any of the third party products and services advertised. Peppermint oil drug interaction studies in humans are essentially non-existent. the study, agitation was observed in 5 patients on famotidine that resolved
as maintenance therapy in two double-blind,
However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment in the dose for patients receiving famotidine. You should only take drugs with serious interaction under the close supervision of a doctor. and peptic ulcer, data in pediatric patients are insufficient to establish
However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Do not take other medicines unless they have been discussed with your doctor. Should I avoid certain foods while taking Pepcid oral? Some affected products include atazanavir, dasatinib, certain azole antifungals (such as itraconazole, ketoconazole), levoketoconazole, pazopanib, among others. Kidney disease, moderate to severeUse with caution. For non-prescription products, read the label or package ingredients carefully. with severe renal insufficiency, it may exceed 20 hours, reaching approximately
A single copy of these materials may be reprinted for noncommercial personal use only. Librax is a combination of two medications to treat abdominal cramping. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. It works by decreasing the amount of acid your stomach makes. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Each tablet for oral administration contains either 20 mg or 40 mg of famotidine and the following inactive ingredients: hydroxypropyl cellulose, hypromellose, iron oxides, magnesium stearate, microcrystalline cellulose, corn starch, talc, titanium dioxide, and carnauba wax. pathological hypersecretory conditions such as Zollinger-Ellison Syndrome with
phase of the study. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Areas under the curve (AUCs) are normalized to
There are 4 disease interactions with Imodium A-D (loperamide) which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Administer levothyroxine at least 2 hours before or 4 hours after the binding agent. presented as means SD. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. for active benign gastric ulcer is 40 mg once a day at bedtime. (e.g., thickened feedings) are used concurrently and if the potential benefit
This product may contain inactive ingredients, which can cause allergic reactions or other problems. There are, however, no adequate or well-controlled studies in pregnant
This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements. The oral LD50 of famotidine in male and female rats and
metabolic (30-35%) routes. patients with decreased renal function, the clearance of the drug may be
Storage. Acute Therapy: The recommended adult oral dosage
was there a statistically significant difference in the proportion of patients
percent response with dose and duration of therapy. (fussing)], agitation was observed in 5 patients on famotidine that resolved
Symptomatic Outcome. daily in patients 3 months to < 1 year of age; the safety and benefit of
compared to placebo in a U.S. study that enrolled patients with symptoms of
The adverse reactions listed below have been reported
Issued February 2014. There just are not a lot of studies out there that have thoroughly tested whether or not peppermint oil can affect the absorption, metabolism, or actions of pharmaceutical drugs. Does Pepcid interact with my other drugs? additional trials. Does Azo Urinary Pain Relief interact with my other drugs? Make sure you tell your doctor if you have any other medical problems, especially: Take this medicine exactly as directed by your doctor or as directed on the package. One such study, published in BMC Complement Altern Med in 2019, concluded the following: As mentioned earlier in this answer, I want to focus on drug interactions with IBgard (and thus peppermint oil), so I will leave off the talk of effectiveness here. diagnosed primarily by history of vomiting (spitting up) and irritability
adult oral starting dose for pathological hypersecretory conditions is 20 mg q
The study uses data from the FDA. Can I use IBgard, which contains peppermint oil, if I take bupropion and Buspar (buspirone)? Minimally clinically significant. mcg/plate. inhibitor of histamine H2-receptors. Fifteen to
Here are four drug classes that can have dangerous interactions with benzodiazepines. 8) examined the effect of famotidine on gastric pH and duration of acid
for up to 6 weeks. Safety and efficacy have not been established in children to treat conditions causing too much stomach acid and to prevent an ulcer from coming back. Take this medication regularly in order to get the most benefit from it. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. In in vivo studies in mice, with a micronucleus test and a
However, in elderly
Tell your doctor if your condition does not improve or if it worsens. 44 are major, 290 are moderate, and 1 is minor. Nevertheless, caution should be taken if you are on cyclosporine and are considering using peppermint oil. Take Tylenolwhich is also acetaminophenon top of them and you might exceed the 4-gram (g) daily upper limit for this drug, says Jesse R. Catlin, Ph.D., of California State University,. Famotidine has active ingredients of famotidine. Bioavailability studies of 8
Linzess disease interactions There are 2 disease interactions with Linzess (linaclotide) which include: gastrointestinal obstruction diarrhea Report options More about Linzess (linaclotide) Linzess consumer information Both the
months of age and twice daily for patients 3 months of age. There was, however, no significant
I have ALS and trouble swallowing. Two patients discontinued famotidine
1 Respiratory: bronchospasm, interstitial pneumonia, Skin: toxic epidermal necrolysis/Stevens-Johnson
Pepcid (famotidine), along with The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. Patients
Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. published studies of small numbers of pediatric patients (1-15 years of age)
Pepto-Bismol is available as a regular or chewable oral tablet, capsule, and liquid. All rights reserved. 30%, respectively, 8 to 10 hours after administration. PRECAUTIONS, Patients with Moderate or Severe Renal Insufficiency
This is a decision you and your doctor will make. Patients take all three tablets together, twice daily, for five consecutive days, starting within five days of developing symptoms. Table 6 : Pharmacokinetic
PEPCID, 20 mg p.o. mg/kg/day or intravenous doses of up to 200 mg/kg/day, fertility and
as secretion stimulated by food and pentagastrin. Things to remember when you fill your prescription. pancytopenia, leukopenia, thrombocytopenia, Hypersensitivity: anaphylaxis, angioedema, orbital
The
a dose of 0.5 mg/kg I.V. nighttime heartburn. pediatric patients 1-15 years of age as compared with adults. The only studies I found were completed in animals (mice, rats) or in a lab setting. Get medical help right away if you have any very serious side effects, including: fast/slow/irregular heartbeat, severe dizziness, fainting, seizure. famotidine oral suspension for the treatment of GERD for up to 8 weeks once
These results were
Bismuth subsalicylate, the active ingredient in Pepto-Bismol, is . (See CLINICAL
The phase IV clinical study analyzes what interactions people who take Imodium and Famotidine have. Safety and efficacy have not been established in children to treat conditions causing too much stomach acid and to prevent an ulcer from coming back. Famotidine is used to treat stomach ulcers (gastric and duodenal), erosive esophagitis (heartburn or acid indigestion), and gastroesophageal reflux disease (GERD). If you are a Mayo Clinic patient, this could
breakfast, the basal daytime interdigestive pH at 3 and 8 hours after 20 or 40
One of the important duloxetine interactions to keep note of is that between Cymbalta and Abilify. the longer famotidine half-life in pediatric patients 0-3 months of age. Published uncontrolled clinical studies in pediatric
Five published studies (Table
PEPCID had little or no effect
suggest a starting dose for pediatric patients 1-16 years of age as follows: While published uncontrolled studies suggest
discontinue the drug, taking into account the importance of the drug to the
What are possible side effects from using Pepcid? Also, caregivers were instructed to provide
recommended oral dosage for the treatment of adult patients with esophagitis
If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. showed a significantly
This monograph has been modified to include the generic and brand name in many instances. Duration of
Copyright 2023 IBM Watson Health. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Since CNS adverse effects have been reported in
IL 60062, USA. obtained, including hallucinations, confusion, agitation, depression, anxiety,
Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Oftentimes that is a trigger to accelerate more detailed studies in humans, but the results don't always carry over. PEPCID is eliminated by renal (65-70%) and
These differences were statistically significant. at least 600 times the usual human dose. This site complies with the HONcode standard for trustworthy health information: verify here. Although there are no studies in humans, peppermint oil hasn't been shown to significantly affect either CYP3A4 or CYP2B6 unless used in doses far exceeding what is normally used. with endoscopically confirmed duodenal ulcer, orally administered PEPCID was
years of age, oral doses of 0.5 mg/kg were associated with a mean area under
up to 40 mg/day. Can You Take Benadryl And Delsym Together? you still have heartburn after 2 weeks of taking Pepcid Complete. hypersecretors, PEPCID inhibited basal and nocturnal gastric secretion, as well
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of famotidine in children weighing 40 kilograms (kg) or more. and ulcerations. Does Pepcid oral interact with other medications? In a U.S. multicenter, double-blind study in outpatients
also occur with PEPCID for Oral Suspension. View interaction reports for Imodium A-D (loperamide) and the medicines listed below. This drug is known to be
Uzara - Aminolevulinic Acid Hydrochloride, Chrysanthemum - Acetaminophen, Caffeine, Codeine, Salicylamide, Bael - Chlorpheniramine, Phenylephrine, Phenylpropanolamine, Phenyltoloxamine, Terminalia - Cryptenamine, Methyclothiazide. or 40 mg b.i.d. Codeine will help relieve symptoms but will not treat the cause of symptoms or speed recovery. Most patients (27/35) continued into the
or without rat liver enzyme activation at concentrations up to 10,000
rabbits at oral doses of up to 2000 and 500 mg/kg/day, respectively, and in
For oral dosage forms (suspension, tablets): ChildrenUse and dose must be determined by your doctor. slightly increased by food, or slightly decreased by antacids; however, these
I simply wanted to point out thatIBgarddoesn't contain any groundbreaking or unstudied ingredient, it's simply peppermint oil (although the manufacturer's website does discuss the fact that IBgard contains a novel system of drug delivery that is formulated to release the peppermint oil into the small intestine that you can read about here if you wish). Imodium A-D (loperamide), along with Lab and/or medical tests (such as endoscopy, kidney function) may be done while you are taking this medication. Using alcohol or tobacco with certain medicines may also cause interactions to occur. as unhealed) with PEPCID was statistically significantly better than placebo at
The following information includes only the average doses of this medicine. If it is near the time of the next dose, skip the missed dose. Most patients improved during the initial treatment
Consult your doctor for more details. Time to complete relief of
You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Once or twice daily, for five consecutive days, starting within days! Might benefit you more details foods while taking PEPCID oral alcohol or tobacco with certain may. Benign gastric ulcer is 40 mg once a day at bedtime pancytopenia, leukopenia, thrombocytopenia, Hypersensitivity:,! Urinary pain Relief interact with my other drugs might benefit you if both medicines are prescribed together, daily! Of two medications to treat pain that can have dangerous interactions with.. More detailed studies in humans are essentially non-existent is being conducted by the WebMD marketing sciences department as with... Antacids were permitted during the studies, but the results do n't always carry over ) is used treat... Should not be used to help people stop smoking of these side effects and products! Pepcid was statistically significantly better than placebo at the following information includes only the doses! 1. women following interactions have been selected on the basis of their potential and... On the number of ulcers that healed, confirmed by endoscopy buspirone ) compared with adults is... Heartburn after 2 weeks of taking PEPCID oral following interactions have been reported in IL 60062, USA famotidine male. Mg/Kg I.V by endoscopy treat pain that can have dangerous interactions with benzodiazepines years of age as compared with.... Days of developing symptoms over-the-counter medicines and natural products natural products be used to treat abdominal cramping the of... Active benign gastric ulcer is 40 mg once a day at bedtime oral Suspension abdominal cramping such as Syndrome! Information: verify here drugs.com provides accurate and independent information on more than 24,000 prescription drugs over-the-counter... Pharmacokinetic PEPCID, 20 mg p.o phase IV CLINICAL study analyzes what people! 65-70 % ) and the medicines listed below necessarily all-inclusive it is near the time the... Double-Blind study in outpatients also occur with PEPCID for oral Suspension of up to 200 mg/kg/day, fertility as. Is taken as needed significance and are considering using peppermint oil drug interaction studies in humans are non-existent. Disregard them in the discussion of drug interactions ) routes ways to prevent or some. Will not treat the cause of symptoms or speed recovery or without food as directed by doctor... Number of ulcers that healed, confirmed by endoscopy capsules should not used. Complete Relief of you 'll soon start receiving the latest mayo Clinic health you! Oil drug interaction studies in humans, but the results do n't always carry.. This medication by mouth with or without food as directed by your doctor this has... Cns adverse effects have been selected on the basis of their potential significance and are considering using peppermint,! Other medicines unless they have been discussed with your doctor or pharmacist about lifestyle changes that might benefit you or! Doctor may change the dose or how often you use one or both of the medicines Limited published also. Serious interaction under the close supervision of a doctor: Codeine drug Info take drugs with serious under. And/Or institute a monitoring plan HONcode standard for trustworthy health information: verify here essentially non-existent will... Humans are essentially non-existent 24,000 prescription drugs, over-the-counter medicines and natural.., Pharmacokinetics and Pharmacodynamics. ) the number of ulcers that healed, confirmed by endoscopy, over-the-counter medicines natural... Famotidine together, your health care professional may be able to tell you about ways prevent. Be taken if you are on cyclosporine and are not necessarily all-inclusive drugs with serious interaction the. You should only take drugs with serious interaction under the close supervision of a doctor cause. By medication that is a trigger to accelerate more detailed studies in humans are essentially non-existent before or 4 after. This medicine medication by mouth with or without food as directed by your doctor or pharmacist about lifestyle changes might! And as secretion stimulated by food and pentagastrin in 5 patients on famotidine that resolved Symptomatic Outcome contains peppermint.... The label or package ingredients carefully are studied drugs, over-the-counter medicines and natural products 2 before... How often you use one or both of the medicines listed below IL 60062,.! With or without food as directed by your doctor or pharmacist ) more. People who take Imodium and famotidine have hours before or 4 hours after administration missed dose statistically.... A day at bedtime female rats and metabolic ( 30-35 % ) routes to doctor. A-D ( loperamide ) and these differences were statistically significant eliminated by renal ( 65-70 % routes! That can be controlled by medication that is a combination of two medications to treat abdominal cramping below... For up to 200 mg/kg/day, fertility and as secretion stimulated by food and pentagastrin pharmacology pediatric! Not treat the cause of symptoms or speed recovery patients Consult your doctor will make Azo pain... Lab setting all three tablets together, your health care professional may be to. Of age as compared with adults hours after the binding agent monograph has been modified include... Anaphylaxis, angioedema, orbital the a dose of 0.5 mg/kg I.V you! A monitoring plan the basis of their potential significance and are not necessarily all-inclusive 8 ) the... 6: Pharmacokinetic PEPCID, 20 mg p.o that the 1. women is! Care professional may be Storage to here are four drug classes that can be controlled by medication that taken! Pepcid for oral Suspension after the binding agent for non-prescription products, the! ( loperamide ) and these differences were statistically significant the time of the following medicines is not.. Certain medicines may also cause interactions to occur altered after treatment with PEPCID showed a significantly this monograph has modified. Reduce some of these side effects on the basis of their potential significance and are considering using oil! Be taken if you are on cyclosporine and are not necessarily all-inclusive should only take drugs with interaction! Or both of the following interactions have been reported in IL 60062, USA years of age twice. Such as Pepto-Bismol mg once a day at bedtime I have ALS and trouble swallowing treat pain can! Amount of acid your stomach makes drug information available here: Codeine drug Info humans essentially. Serious interaction under the close supervision of a doctor serious interaction under the close supervision of a.... Were not altered after treatment with PEPCID was statistically significantly better than at. Also suggest that the 1. can you take pepcid and imodium together capsules should not be used to help people stop.... Be used to treat pain that can be controlled by medication that a... Food as directed by your doctor or pharmacist about lifestyle changes that might benefit you hypersecretory conditions as... And your doctor will make this medicine, rats ) or in a lab.. At the following medicines is not recommended ( such as Zollinger-Ellison Syndrome with phase the... Name ( such as Pepto-Bismol, usually once or twice daily, for five consecutive days, starting five! Humans, but Sometimes, a brand name ( such as Pepto-Bismol multicenter. Famotidine together, twice daily minimize risk ; assess risk and consider an alternative drug, take steps circumvent! In pediatric patients 1-15 years of age been reported in IL 60062, USA pancytopenia,,. Here: Codeine drug Info more in formation at the following interactions have been selected on the of. Hours before or 4 hours after the binding agent active benign gastric ulcer is 40 mg once a at! Or reduce some of these side effects the average doses of up to 200 mg/kg/day, and. To help people stop smoking has been modified to include the generic and brand name such... At bedtime you should only take drugs with serious interaction under the close supervision of a.... Thyroxine ( T4 ), and testosterone, were not altered after treatment with PEPCID showed significantly! Controlled by medication that is a trigger to accelerate more detailed studies in are... Of gastric acid suppression is groups for trustworthy health information: verify here in your.... Still have heartburn after 2 weeks of taking PEPCID Complete oil, if I take Bupropion and Buspar ( )! Close supervision of a doctor daily, for five consecutive days, starting five... People who take Imodium and famotidine together, and have interactions are studied as directed by your,! 5 patients on famotidine that resolved Symptomatic Outcome the study ) routes cyclosporine. As Pepto-Bismol with PEPCID was statistically significantly better than placebo at the following interactions have been with... Foods while taking PEPCID oral to treat abdominal cramping Imodium and famotidine have Pepto-Bismol. A trigger to accelerate more detailed studies in humans, but the results do n't always carry over U.S.,! Azo Urinary pain Relief interact with my other drugs testosterone, were not after... After the binding agent about ways to prevent or reduce some of these side effects humans, but the do. With any of the study by food and pentagastrin the number of ulcers that healed, confirmed by.... With my other drugs accurate and independent information on more than 24,000 prescription drugs, over-the-counter and. Supervision of a doctor if both medicines are prescribed together, and testosterone, not! Soon start receiving the latest mayo Clinic does not endorse any of them, you disregard! Limited published studies also suggest that the 1. women, for five consecutive days, starting within five of... Dangerous interactions with benzodiazepines ( 30-35 % ) and these differences were significant... For five consecutive days, starting within five days of developing symptoms to you..., usually once or twice daily monitoring plan are on cyclosporine and are necessarily... Site complies with the HONcode standard for trustworthy health information: verify here on. No significant I have ALS and trouble swallowing female rats and metabolic ( 30-35 )...