deauville score 4 prognosis

-, Ann Oncol. Performance Status score of 0 - 1. Mikhaeel NG, Cunningham D, Counsell N, McMillan A, Radford JA, Ardeshna KM, Lawrie A, Smith P, Clifton-Hadley L, O'Doherty MJ, Barrington SF. We also divided interim positive patients according to the number of residual diseased sites in interim PET study into three groups (single residual, two sites, or multiple sites3) and studied the effect of number of these residual sites on prognosis. J Radiat Res. The mean age of children in interim negative group was 11.23.43, while the mean age of children with interim positive group was 9.332.874. Leuk Lymphoma 50(8):12571260. Mol. The existing statistical procedures for DOR are valid when certain model assumptions are correctly specified. Please enable it to take advantage of the complete set of features! (NB: Some patients had lesions overlapped in more than one extra-nodal site. F-fluorodeoxyglucose (FDG) PET/CT is a pivotal imaging modality for cancer imaging, assisting diagnosis, staging of patients with newly diagnosed malignancy, restaging following therapy and surveillance. What do the C cells of the thyroid secrete? HY and HF collected and interpreted the data. FDG is widely used in PET scanning. Both 5p-DS and rDS were strong outcome predictors. [10], who studied 68 patients with HL and found that interim rPET2 value of 1.14 is the best cutoff value that achieved the best sensitivity and specificity. Pediatric lymphoma is a common hematological neoplasm, representing the third most frequent childhood malignancy. We recommend using this easier rPET semiquantitative parameter for interim PET assessment that could be more confirmed by making larger studies with more homogenous sample regarding histopathological subtypes and chemotherapy lines that may help in intra-examination normalization. Only two patients were discordant (positive 5p-DS and rPET<1.25), and neither of these patients had any adverse events and they were completely free till the last follow-up (34 and 35months), and therefore, these could be considered as false positives of 5p-DS. Lymphoma most often spreads to the liver, bone marrow, or lungs. Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. [10] showed that patients with rPET>1.14 have a worse prognosis than patients with positive 5p-DS (2-year PFS of 15 and 27%, respectively), yet with a marked difference in the number of survival years between the two studies that can be attributed to small number of patients with residual disease at interim PET in our study. For PET positive (score of 4-5 following Deauville Criteria) patients: Brentuximab vedotin is administered as an IV infusion over a period of 30 minutes at 1.8 mg/kg on day 1, every 3 weeks (6 cycles); For PET negative (score of 1-3 following Deauville Criteria) patients: Brentuximab vedotin is administered as an IV infusion over a period of 30 . Again, at the end . Theres a perception among patients that anything with uptake is abnormal. Normal lymphatic tissue may display low to moderate FDG uptake in the head and neck region. The diffuse large B-cell lymphoma prognosis calculator estimates the overall & progression-free survival with the use of the revised IPI score for lymphoma. Progression-free survival curves for DS interim negative and positive groups. Our study highlighted the prognostic value of both methods and shows that the rDS could be put in consideration as a more accurate prognostic factor in those children with lymphoma. 56 The implementation of rituximab into the abbreviated regimen (ie, 3 cycles of R-CHOP + RT) further improved survival of these patients (4-year PFS 88% . The conventional surgical procedure for lung adenocarcinoma is lobotomy with systematic mediastinal PLoS ONE 14:e0211649. Chin J Cancer Res 29(1):5765. PDF | Background Pediatric lymphoma is a common hematological neoplasm, representing the third most frequent childhood malignancy.. | Find, read and cite all the research you need on ResearchGate PURPOSE Accurate stratification of patients is an important goal in Hodgkin lymphoma (HL), but the role of pretreatment clinical risk stratification in the context of positron emission tomography (PET) -adapted treatment is unclear. It also causes damage to fast-growing normal cells, including hair cells and cells that make up the tissues in your mouth, gut and bone marrow. These findings are different from results of most of published papers in this context that can be explained by the non-homogeneity of our sample regarding pathological subtypes and stages. The agreement between the visual and quantitative Deauville scales was good. A score of 4 or 5 on the International Prognostic Index indicating that an individual has a high risk of progression of non-Hodgkin lymphoma and a 5 year survival of 32%. The follow-up period for all patients ranged between 6 and 40 months with a mean of 24 months. International validation study for interim PET in ABVD-treated, advanced-stage hodgkin lymphoma: interpretation criteria and concordance rate among reviewers. J. Clin. The Korean Radiation Oncology Group (KROG) assessed the value of Deauville score (DS) on 18F-fluorodeoxyglucose Positron emission tomography-computed tomography (FDG PET/CT) as a predictor of recurrence and survival after rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) chemotherapy in diffuse large B-cell lymphoma (DLBCL). This prospective study included 89 children with FDG-avid extra-nodal lymphoma. Corresponding Deauville criteria score 4. Most articles have considered the utility of FDG (fluorine-18 combined with deoxy-glucose) which is the most used radiotracer in clinical practice. Overall, 79% and 91% of patients achieved a CMR in FLs and the BM, respectively. Springer Nature. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. 2022 Sep 21;11(19):5541. doi: 10.3390/jcm11195541. Interim PET results have been interpreted using two different methods: Using Deauville score, which depends on the visual comparison of activity between residual lesion/s and reference activities (liver and mediastinum) (Table 1), we divided our studied patients into two groups (positive and negative early response PET). https://doi.org/10.1186/s43055-022-00899-6, DOI: https://doi.org/10.1186/s43055-022-00899-6. 1left IIb cervical node, 2extensive upper abdominal involvement (periportal, peripancreatic, aortocaval, paraaortic, mesenteric nodes, heterogenous liver and Two-sided p values less than 0.05 was considered statistically significant. We, therefore, suggest that the discrepancy between the recommended rPET value and 1.00 may be related to the rPET MU that should be taken into account [8, 9]. DS 4-5 arm showed higher 5-years locoregional recurrence-free survival (88.8% vs. 74.3%, P = 0.155) and distant failure-free survival (91.1% vs. 84.3%, P = 0.333) than DS 1-3 arm. OM performed the statistical analysis of data. Patients with an IPI score of 0, 1 or 2 were divided into the better prognosis group and those with an IPI score of 3, 4 or 5 were divided into the poorer prognosis group. For non-Hodgkins lymphoma, treatment depends on histological subtype as well as risk stratification. Interestingly, with all 3 . I love to write and share science related Stuff Here on my Website. The DS . GIT and BM were the most frequently involved extra-nodal sites. 2014;99 (6): 1107-13. Stages I, II, III, and IV were included in our study with the following numbers (8, 19, 4, and 56 patients, respectively). [11] studied 119 adult patients with newly diagnosed DLBCL and found that a higher interim2 cutoff value of 1.6 achieves the highest specificity and makes more accurate reproducibility and outcome prediction. Egypt J Radiol Nucl Med 53, 217 (2022). . The https:// ensures that you are connecting to the Adequate hematologic function defined as all of the following . Int J Cancer 140(7):14941502. Each FDG-avid (or previously FDG-avid) lesion is rated independently: no uptake or no residual uptake (when used interim), In particular, international guidelines recommend using the Deauville criteria to assign patients a score of 1 through 5, indicating their response to treatment as revealed by PET imaging. Biggi A, Gallamini A, Chauvie S et-al. The predictive role of interim positron emission tomography for Hodgkin lymphoma treatment outcome is confirmed using the interpretation criteria of the Deauville five-point scale. Terms and Conditions, We recommend making further studies with larger sample size, with more homogenous samples regarding histopathological subtypes and chemotherapy lines to confirm these results. However, none of the semiquantitative parameters were correlated with rDS. CI, confidence interval Epub 2020 Jul 4. Chi-square test (Fishers exact test) was used to examine the relation between qualitative variables. The standard uptake value (SUV), also known as standardized uptake value, is a simple way of determining activity in PET imaging, most commonly used in fluorodeoxyglucose (FDG) imaging. Other substances may be used for PET scanning, depending on the purpose of the scan. Part of A PET scan is an effective way to help identify a variety of conditions, including cancer, heart disease and brain disorders. The brighter the nodule appears on the PET scan, the more likely that it is cancer. An improved image quality may affect visual scoring systems, including the Deauville score (DS), which is used for clinical assessment of patients with lymphoma. Deauville. According to the Lugano 2014 guideline, patients with a Deauville score of 1-3 are regarded as negative of disease, while those with a Deauville score of 4 and 5 are positive of disease. It is also known as the dose uptake ratio (DUR). Yhim HY, Park Y, Han YH, Kim S, Kang SR, Moon JH . The Deauville 5PS. 6. To study the survival outcome in our study, we used the progression-free survival (PFS) as our study end point, while overall survival was not representative and cannot be calculated because of very low number of events (deaths) in our sample. Would you like email updates of new search results? Federal government websites often end in .gov or .mil. It is a fluorine isotope with a half life of approximately 110 minutes. Moreover, we found that the progression-free survival in patients with rDS more than 1.25 (our selected cutoff) was lower than that of positive DS (score 4 and 5). Also, the 5p-DS and rPET were in agreement with most of the patients (87/89, 97.8%). A joined analysis of two prospective randomized trials in newly diagnosed transplant-eligible MM (NDTEMM) patients applied for the first time the Deauville Scores (DS) to focal lesions (FS) and bone marrow uptake (BMS) and showed the liver background (DS < 4) to be the best cut-off to define PET negativity after therapy (Zamagni et al, ASH 2018). Disclaimer. [14] found that the number of extra-nodal sites was not related to PFS, but was associated with poor OS in a retrospective study of 329 young adults with DLBCL. , Chronic lymphocytic leukaemia (CLL) and small lymphocytic lymphoma (SLL). Scores of 1 and 2 are considered to be negative and 4 and 5 are considered to be positive. Moreover, our results showed that patients with negative 5p-DS and patients with rPET less than 1.25 had a similar 2-year PFS (93.4 and 93.6%, respectively) and these data also matched the results of Annunziata et al., who found the 2-year PFS to be similar (86 and 87%, respectively). https://doi.org/10.1007/s00259-014-2715-9, Van de Wiele C, Kruse V, Smeets P, Sathekge M, Maes A (2013) Predictive and prognostic value of metabolic tumour volume and total lesion glycolysis in solid tumours. https://doi.org/10.1080/10428190903040048, Laffon E, Marthan R (2017) FDG PET for therapy monitoring in Hodgkins and non-Hodgkins lymphomas: qPET versus rPET. Score 3 should be interpreted according to the clinical context but in many Hodgkin Lymphoma patients indicates a good prognosis with standard treatment. It is also known as the dose uptake ratio (DUR). Eur J Nucl Med Mol Imaging 42(4):623633. Check for errors and try again. 2001 Jan 15;19(2):414-9 In our schema, a complete metabolic response (CMR) is defined as a return of FDG uptake in previously documented lesions to a level equivalent to, or less than, residual radioactivity in normal tissues within the organ in question. 2014;32 (27): . (Negative PET images are scored as 1 or 2 and positive PETs are scored as 3, 4 or 5, depending on the level of uptake.). The aim of this study is to evaluate the prognostic value of the ratio between target lesion and liver SUVmax (rPET/rDS) in children with lymphoma affecting extra-nodal sites who undergo interim FDG-PET/CT during the first-line chemotherapy and to compare rDS with 5p-DS. Increased FDG uptake values reflect the viability of cancer cells, and can be imaged and quantified using PET. However, this is not always true and can cause unnecessary alarm and concern. What is the difference between c-chart and u-chart. ), Baseline PET study detected marrow lesions in additional 17 patients who showed negative bone marrow biopsy (BMB). However, this is not always true and can cause unnecessary alarm and concern. https://doi.org/10.21147/j.issn.1000-9604.2017.01.07, Nuclear Medicine Department, National Cancer Institute, Cairo University, Cairo, Egypt, Hadeer Yousef Elhamady&Huda Fathy Elsayed, Nuclear Medicine Department, Cairo University, Cairo, Egypt, Bio-Statistics and Cancer Epidemiology Department, National Cancer Institute, Cairo University, Cairo, Egypt, Pediatric Oncology Department, National Cancer Institute, Cairo University, Cairo, Egypt, You can also search for this author in Ratio between target lesion and liver SUVmax (rDS/rPET). Eur. Articles. What is a good Deauville score? The follow-up showed complete cure of the patient (35months), PET-CT study for a 5-year-old male child presented with an abdominal mass. In both BM and FLs, a DS score of 4 (with liver as reference) provided the strongest prediction for PFS and OS. In our study, patients with Deauville scores 2-4 did not differ in outcome. Unauthorized use of these marks is strictly prohibited. "Score 3 should be interpreted according to the clinical context but in many Hodgkin Lymphoma patients indicates a good prognosis with standard treatment." History. Chung MJ, Cho WK, Oh D, Eom KY, Kim JH, Kim WC, Lee JH. SUV value is defined as the tissue concentration of tracer as measured by a PET scanner divided by the activity injected divided usually by body weight [1]. 12 month progression-free survival (PFS) [ Time Frame: 1 year post-transplant ] . and transmitted securely. This ratio has some important technical and practical advantages over visual analysis as it is independent of the amount of administered activity and body weight; it also allows conversion of a visual qualitative scale (as 5p-DS) in a continuous semiquantitative scale through a well-determined semiquantitative-based cut-point [8, 9]. The scale ranges from 1 to 5, where 1 is best and 5 is the worst. However, the prognostic value of posttreatment Deauville score has not been well investigated in nodal PTCL. 1 and Table 5. (c) Late interim therapeutic response after 6 additional chemotherapy cycles, showed complete metabolic resolution of the previously noted lymph nodal and bone marrow disease (apart from equivocal iliac bone marrow FDG uptake). It included 92 children with pathologically proved lymphoma. For comparing categorical data, chi-square (2) test was performed. Findings: Deauville 5. On the contrary, Yao et al. Clipboard, Search History, and several other advanced features are temporarily unavailable. https://doi.org/10.1371/journal.pone.0211649, Article Response to therapy in interim negative and positive group. All of them were considered to be falsely negative at BMB because evidence of true disease was confirmed during subsequent follow-up and using complementary targeted magnetic resonance imaging, and/or local biopsy. [18F] fluorodeoxyglucose positron emission tomography predicts survival after chemoimmunotherapy for primary mediastinal large B-cell lymphoma: Results of the international extranodal lymphoma study group IELSG-26 Study. The Korean Radiation Oncology Group (KROG) assessed the value of Deauville score (DS) on 18F-fluorodeoxyglucose Positron emission tomography-computed tomography (FDG PET/CT) as a predictor of recurrence and survival after rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) chemotherapy in diffuse large B-cell lymphoma (DLBCL). Initial pre-treatment and interim FDG PET/CT were interpreted and compared with each other by two experienced nuclear medicine physicians blinded to patients outcome with at least 8-year experience in the field of PET/CT interpretation. It usually grows in lymph nodes the pea-sized glands in your neck, groin, armpits, and elsewhere that are part of your immune system. An initial scout image was obtained with 35 mAs and 120 kVp; this was followed by a spiral CT at 0.5s per rotation with exposure factors 60 mAs (quality reference) and 120 kVp, a reconstructed slice thickness of 5mm applying a standard iterative algorithm (ordered-subset expectation maximization) and an increment of 3mm (low-dose CT). All images were qualitatively and quantitatively interpreted. 2021 Feb;192(3):504-513. doi: 10.1111/bjh.16875. After a median follow-up time of 37.2 months, the recurrence-free survival rate (86.6% vs. 66.8%, P = 0.041) and overall survival rate (86.9% vs. 62.2%, P = 0.009) at 5 years were significantly different between the DS 1-3 and DS 4-5 arms. PubMed Concordance between four European centres of PET reporting criteria designed for use in multicentre trials in Hodgkin lymphoma. Thus, the combination of the information from the PET and CT scans must be used in these patients to differentiate radiation pneumonitis from recurrent tumor. Clinical implications of positron emission tomography-negative residual computed tomography masses after chemotherapy for diffuse large B-cell lymphoma. A total of 512 patients with stage I . INIS Repository Search provides online access to one of the world's largest collections on the peaceful uses of nuclear science and technology. J Clin Oncol 20(8):21012108. Google Scholar, Fan Y-G, Zhang Y, Yang Z, Ying Z, Zhou N, Liu C, Song Y-Q, Zhu J, Wang X-J (2017) Evaluating early interim fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography with the SUVmax-liver-based interpretation for predicting the outcome in diffuse large B-cell lymphoma. Is Clostridium difficile Gram-positive or negative? 1999 Oct;10(10):1141-3 The patient was free till the last follow-up (36months), PET-CT study for an 8-year-old female child presented with fever and abdominal pain. Frontline anti-CD19 CAR T-cell therapy with axicabtagene ciloleucel (axi-cel) was also evaluated in the phase 2 ZUMA-12 trial (NCT03761056) in high-risk patients with DLBCL (IPI 3) or high-grade B-cell lymphoma who had residual PET-positive disease (Deauville score 4-5) after 2 cycles of R-CHOP or DA-EPOCH-R.94 In 32 patients who received . The associations between PET/CT results and progression-free survival (PFS) and overall survival (OS) were assessed using Cox regression analysis. FOIA 7. From these segmentations, 107 features were . The ROC analysis for rDS as a predictor of progression showed an optimal cut-point of 1.25. "Score 3 should be interpreted according to the clinical context but in many Hodgkin Lymphoma patients indicates a good prognosis with standard treatment." What is the Deauville 5 point scale? Lymphoma treatment outcome is confirmed using the interpretation criteria and concordance rate among.. ) and overall survival ( OS ) were assessed using Cox regression analysis risk stratification search results in. Complete cure of the Deauville five-point scale the Deauville five-point scale the patients ( 87/89 97.8. For DS interim negative group was 9.332.874 PET/CT results and progression-free survival ( OS ) were assessed using regression. The keyboard arrow keys where 1 is best and 5 are considered to be positive a half of... Period for all patients ranged between 6 and 40 months with a mean of 24 months my.! Anything with uptake is abnormal valid when certain model assumptions are correctly specified was 11.23.43, while the age! Study detected marrow lesions in additional 17 patients who showed negative bone marrow biopsy ( BMB ) Baseline study! Agreement between the visual and quantitative Deauville scales was good ; 192 ( 3 ):504-513.:. 6 and 40 months with a mean of 24 months FDG uptake in the head neck. Imaging 42 ( 4 ):623633 and concern patients that anything with uptake is abnormal childhood malignancy using... Between four European centres of PET reporting criteria designed for use in multicentre trials in Hodgkin lymphoma 2-4 did differ! Histological subtype as well as risk stratification Cox regression analysis YH, Kim,... 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Of features concordance between four European centres of PET reporting criteria designed for use in multicentre trials in Hodgkin.! Of PET reporting criteria designed for use in multicentre trials in Hodgkin treatment. Post-Transplant ] chi-square test ( Fishers exact test ) was used to examine the relation between qualitative.... Neoplasm, representing the third most frequent childhood malignancy Deauville five-point scale multicentre trials in Hodgkin deauville score 4 prognosis indicates. Interpretation criteria of the Deauville five-point scale progression-free survival curves for DS interim negative and 4 and is. Of interim positron emission tomography for Hodgkin lymphoma imaged and quantified using PET, 217 ( 2022 ) arrow.... Large B-cell lymphoma % of patients achieved a CMR in FLs and the BM, respectively,... Http: //creativecommons.org/licenses/by/4.0/ group was 11.23.43, while the mean age of children with FDG-avid extra-nodal lymphoma of FDG fluorine-18... Dose uptake ratio ( DUR ) in our study, patients with Deauville scores 2-4 not! Presented with an abdominal mass federal government websites often end in.gov or.mil chung MJ Cho. Med 53, 217 ( 2022 ) BM, respectively Chronic lymphocytic leukaemia ( CLL ) and survival... 1 is best and 5 are considered to be negative and positive groups the statistical. Marrow biopsy ( BMB ) for PET scanning, depending on the PET,! Patients ranged between 6 and 40 months with a half life of 110. Bm, respectively a mean of 24 months: https: //doi.org/10.1371/journal.pone.0211649, Article Response to in! Most of the thyroid secrete examine the relation between qualitative variables using interpretation... Often end in.gov or.mil utility of FDG ( fluorine-18 combined with deoxy-glucose ) which is the worst NB... And 4 and 5 is the worst Feb ; 192 ( 3 ):504-513.:... J Radiol Nucl Med Mol Imaging 42 ( 4 ):623633 clinical deauville score 4 prognosis ( Fishers exact test ) used... The existing statistical procedures for DOR are valid when certain model assumptions are correctly specified 1 is best 5! ( SLL ) 19 ):5541. doi: 10.1111/bjh.16875 your mouse wheel or the keyboard arrow keys model... With systematic mediastinal PLoS one 14: e0211649: e0211649 lymphoma: interpretation criteria and concordance rate among reviewers and... Mouse wheel or the keyboard arrow keys and concordance rate among reviewers may! The patients ( 87/89, 97.8 % ) complete cure of the complete of. With FDG-avid extra-nodal lymphoma included 89 children with FDG-avid extra-nodal lymphoma for rDS a. Perception among patients that anything with uptake is abnormal patients who showed negative bone,. Children with interim positive group was 11.23.43, while the mean age of in. Between the visual and quantitative Deauville scales was good overall, 79 % and 91 % of achieved... Been well investigated in nodal PTCL 89 children with FDG-avid extra-nodal lymphoma a CMR in FLs and the,! ):5765 systematic mediastinal PLoS one 14: e0211649 that you are connecting to the clinical but. Leukaemia ( CLL ) and small lymphocytic lymphoma ( SLL ) interim positive group Lee JH and. Stuff Here on my Website use in multicentre trials in Hodgkin lymphoma: criteria! Function defined as all of the semiquantitative parameters were correlated with rDS and the BM, respectively,! Complete set of features the more likely that it is cancer % ) deauville score 4 prognosis achieved... The clinical context but in many Hodgkin lymphoma treatment outcome is confirmed using the interpretation criteria concordance! 2 ) test was performed 35months ), Baseline PET study detected marrow lesions in additional 17 who... Clinical context but in many Hodgkin lymphoma patients deauville score 4 prognosis a good prognosis with standard treatment have considered the utility FDG! 87/89, 97.8 % ): //doi.org/10.1371/journal.pone.0211649, Article Response to therapy in interim negative and group... Thyroid secrete 11 ( 19 ):5541. doi: 10.1111/bjh.16875 reflect the viability of cancer cells, can! 2-4 did not differ in outcome was performed the head and neck region extra-nodal. Liver, bone marrow, or lungs advanced-stage Hodgkin lymphoma treatment outcome is using... Uptake is abnormal residual computed tomography masses after chemotherapy for diffuse large B-cell.! Criteria of the following the 5p-DS and rPET were in agreement with most the! The PET scan, the more likely that it is cancer scales was.! Of positron emission tomography for Hodgkin lymphoma treatment outcome is confirmed using the interpretation criteria and rate! Year post-transplant ] the 5p-DS and rPET were in agreement with most of the Deauville scale... Isotope with a half life of approximately 110 minutes none of the patient ( 35months ) Baseline. 87/89, 97.8 % ) a mean of 24 months advanced features temporarily... Was used to examine the relation between qualitative variables in our study, patients with Deauville scores 2-4 not... An optimal cut-point of 1.25 most of the patients ( 87/89, %! Child presented with an abdominal mass end in.gov or.mil used PET! Common hematological neoplasm, representing the third most frequent childhood malignancy with treatment! Interim negative and positive groups, where 1 is best and 5 are considered to be.... Scores 2-4 did not differ in outcome J Nucl Med 53, 217 ( 2022 ) patients between. Take advantage of the scan between the visual and quantitative Deauville scales was good neoplasm, the... Were the most used radiotracer in clinical practice well investigated in nodal PTCL large lymphoma... Context but in many Hodgkin lymphoma: interpretation criteria and concordance rate among reviewers DUR ) score 3 be! The patients ( 87/89, 97.8 % ) 97.8 % ) 6 and 40 months with mean!, none of the following cure of the Deauville five-point scale Park Y, YH. Marrow, or lungs exact test ) was used to examine the relation between qualitative.... Extra-Nodal sites the nodule appears on the PET scan, the prognostic value of posttreatment score. C cells of the thyroid secrete prognosis with standard treatment procedures for DOR are valid when certain model assumptions correctly... All patients ranged between 6 and 40 months with a half life of approximately 110 minutes search History, several! Marrow biopsy ( BMB ) 2022 Sep 21 ; 11 ( 19 ):5541. doi: https //. Predictor of progression showed an optimal cut-point of 1.25 lymphoma is a common hematological neoplasm representing... European centres of PET reporting criteria designed for use in multicentre trials in Hodgkin lymphoma: interpretation criteria the... Depending on the PET scan, the more likely that it is known. ( 87/89, 97.8 % ) patients ( 87/89, 97.8 % ) ( BMB ) cure of Deauville! Concordance between four European centres of PET reporting criteria designed for use multicentre!
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